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1

Myotoxicity of statins: Mechanism of action

du Souich, Patrick, Roederer, Ghislaine, Dufour, Robert

Journal:

Pharmacology & Therapeutics

Year:

2017

Language:

english

File:

PDF, 988 KB

english, 2017

2

Pharmacokinetic and clinical parameters of zopiclone and trimipramine when administered simultaneously to volunteers

Dr. G. Caille, P. Du Souich, J. Spenard, Y. Lacasse, M. Vezina

Journal:

Biopharmaceutics & Drug Disposition

Year:

1984

Language:

english

File:

PDF, 421 KB

english, 1984

3

Pharmacokinetics and pharmacodynamics of a slow-release formulation of diltiazem after the administration of a single and repeated doses to healthy volunteers

M. Lefebvre, Y. Lacasse, J. Spénard, D. Geadah, R. Moisan, D. Gossard, H. Landriault, P. Du Souich, C. Caillé

Journal:

Biopharmaceutics & Drug Disposition

Year:

1994

Language:

english

File:

PDF, 782 KB

english, 1994

4

Signal transduction pathways implicated in the decrease in CYP1A1, 1A2 and 3A6 activity produced by serum from rabbits and humans with an inflammatory reaction

Mihaela Levitchi, Caroline Fradette, Anne-Marie Bleau, Dorothée Michaud, Oksana Kourylko, Mathieu Arcand, Patrick du Souich

Journal:

Biochemical Pharmacology

Year:

2004

Language:

english

File:

PDF, 314 KB

english, 2004

5

Immunomodulatory and anti-inflammatory effects of chondroitin sulphate

Patrick Du Souich, Antonio G. García, Josep Vergés, Eulàlia Montell

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 7.69 MB

english, 2009

6

Pharmacokinetic and pharmacodynamic effects of midodrine on blood pressure, the autonomic nervous system, and plasma natriuretic peptides: a prospective, randomized, single-blind, two-period, crossover, placebo-controlled study

Maxime Lamarre-Cliche, Patrick du Souich, Jacques de Champlain, Pierre Larochelle

Journal:

Clinical Therapeutics

Year:

2008

Language:

english

File:

PDF, 685 KB

english, 2008

7

Complex translocation disrupting TCF4 and altering TCF4 isoform expression segregates as mild autosomal dominant intellectual disability

Maduro, Valerie, Pusey, Barbara N., Cherukuri, Praveen F., Atkins, Paul, du Souich, Christèle, Rupps, Rosemarie, Limbos, Marjolaine, Adams, David R., Bhatt, Samarth S., Eydoux, Patrice, Links, Amanda

Journal:

Orphanet Journal of Rare Diseases

Year:

2016

Language:

english

File:

PDF, 1.41 MB

english, 2016

8

The cost and diagnostic yield of exome sequencing for children with suspected genetic disorders: a benchmarking study

Dragojlovic, Nick, Elliott, Alison M, Adam, Shelin, van Karnebeek, Clara, Lehman, Anna, Mwenifumbo, Jill C, Nelson, Tanya N, du Souich, Christèle, Friedman, Jan M, Lynd, Larry D

Journal:

Genetics in Medicine

Year:

2018

Language:

english

File:

PDF, 331 KB

english, 2018

9

A novel syndrome with psychiatric features and review of malformation syndromes with psychiatric disorders

Christèle du Souich, Jehannine C. Austin, Robin Friedlander, Cornelius F. Boerkoel

Journal:

American Journal of Medical Genetics Part A

Year:

2009

Language:

english

File:

PDF, 584 KB

english, 2009

10

Characterization of a new X-linked mental retardation syndrome with microcephaly, cortical malformation, and thin habitus

Christèle du Souich, Athena Chou, Jingyi Yin, Tracey Oh, Tanya N. Nelson, Jane Hurlburt, Laura Arbour, Robin Friedlander, Barbara C. McGillivray, Nataliya Tyshchenko, Andreas Rump, Kenneth J. Poskitt,

Journal:

American Journal of Medical Genetics Part A

Year:

2009

Language:

english

File:

PDF, 257 KB

english, 2009

11

Minimal genotype–phenotype correlation for small deletions within distal 1p36

A. Buck, C. du Souich, Cornelius F. Boerkoel

Journal:

American Journal of Medical Genetics Part A

Year:

2011

Language:

english

File:

PDF, 1.47 MB

english, 2011

12

Possible relationship of cranial traumatic injuries with violence in the south-east Iberian Peninsula from the Neolithic to the Bronze Age

S.A. Jiménez-Brobeil, Ph. du Souich, I. Al Oumaoui

Journal:

American Journal of Physical Anthropology

Year:

2009

Language:

english

File:

PDF, 406 KB

english, 2009

13

The effect of administration of phenytoin on the pharmacokinetics of isoxicam

Dr G. Caillé, P. du Souich, L. Larivière, M. Vézina, Y. Lacasse

Journal:

Biopharmaceutics & Drug Disposition

Year:

1987

Language:

english

File:

PDF, 258 KB

english, 1987

14

Sulfamethazine absorption and disposition: Effect of surgical procedures for gastroduodenal ulcers

Rosario Calvo, Sebastian Sarabia, Raimundo Carlos, Patrick Du Souich

Journal:

Biopharmaceutics & Drug Disposition

Year:

1987

Language:

english

File:

PDF, 471 KB

english, 1987

15

Single dose pharmacokinetics of ketoprofen, indomethacin, and naproxen taken alone or with sucralfate

G. Caillé, P. du Souich, P. Gervais, J.-G. Besner

Journal:

Biopharmaceutics & Drug Disposition

Year:

1987

Language:

english

File:

PDF, 517 KB

english, 1987

16

Pharmacokinetic interaction between flurbiprofen and antacids in healthy volunteers

Dr. G. Caillé, P. du Souich, M. Vézina, S. R. Pollock, D. J. Stalker

Journal:

Biopharmaceutics & Drug Disposition

Year:

1989

Language:

english

File:

PDF, 411 KB

english, 1989

17

Influence of food on the bioavailability of diltiazem and two of its metabolites following the administration of conventional tablets and slow-release capsules

P. Du Souich, N. Lery, L. Lery, F. Varin, S. Boucher, M. Vezina, D. Pilon, J. Spenard, G. Caillé

Journal:

Biopharmaceutics & Drug Disposition

Year:

1990

Language:

english

File:

PDF, 617 KB

english, 1990

18

Effects of cefotaxime on the serum protein binding of sulfisoxazole

P. Du Souich, R. Calvo, Dr. S. Erill

Journal:

Biopharmaceutics & Drug Disposition

Year:

1990

Language:

english

File:

PDF, 434 KB

english, 1990

19

Pharmacodynamics as a tool to assess the bioequivalence of nonystemically available drugs: Size of the sample required

Patrick Du Souich, Jean-Guy Besner, Gilles Caille

Journal:

Biopharmaceutics & Drug Disposition

Year:

1992

Language:

english

File:

PDF, 502 KB

english, 1992

20

Effect of omeprazole on oral and intravenous RS-methadone pharmacokinetics and pharmacodynamics in the rat

M. Angeles Carlos, Patrick Du Souich, Raimundo Carlos, Elena Suarez, John C. Lukas, Rosario Calvo

Journal:

Journal of Pharmaceutical Sciences

Year:

2002

Language:

english

File:

PDF, 150 KB

english, 2002

21

Absolute drug bioavailability II: Evaluation of renal clearance perturbation method using literature data assuring a fraction absorbed of unity

David Lalka, P. du Souich, A. J. McLean, Milo Gibaldi

Journal:

Journal of Pharmaceutical Sciences

Year:

1978

Language:

english

File:

PDF, 257 KB

english, 1978

22

Cytochrome P-450 content and activity after cold storage of rat hepatocytes in university of wisconsin and sodium-lactobionate-sucrose solutions

Halima Serrar, Ayman El-Kadi, Patrick Du Souich, Pierre Haddad

Journal:

Liver Transplantation

Year:

1999

Language:

english

File:

PDF, 137 KB

english, 1999

23

Some types of vertebral pathologies in the Argar Culture (Bronze Age, SE Spain)

S. A. Jiménez-Brobeil, I. Al Oumaoui, Ph. du Souich

Journal:

International Journal of Osteoarchaeology

Year:

2010

Language:

english

File:

PDF, 344 KB

english, 2010

24

Markers of activity patterns in some populations of the Iberian Peninsula

I. al-Oumaoui, S. Jiménez-Brobeil, P. du Souich

Journal:

International Journal of Osteoarchaeology

Year:

2004

Language:

english

File:

PDF, 464 KB

english, 2004

25

Childhood trauma in several populations from the Iberian Peninsula

S. A. Jiménez-Brobeil, I. Al Oumaoui, Ph. du Souich

Journal:

International Journal of Osteoarchaeology

Year:

2007

Language:

english

File:

PDF, 220 KB

english, 2007

26

Analysis of albuterol in human plasma based on immunoaffinity chromatograhic clean-up combined with high-performance liquid chromatography with fluorimetric detection

Huy Ong, Albert Adam, Sylvie Perreault, Sylvie Marleau, Monique Bellemare, Patrick Du Souich, Normand Beaulieu

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1989

Language:

english

File:

PDF, 587 KB

english, 1989

27

Effect of acute and chronic moderate hypoxia on the kinetics of lidocaine and its metabolites and on regional blood flow

P. du Souich, C. Saunier, D. Hartemann, M. Allam

Journal:

Pulmonary Pharmacology

Year:

1992

Language:

english

File:

PDF, 638 KB

english, 1992

28

Simple and rapid radioimmunoassay for the routine determination of vasopressin in plasma

Patrice Larose, Huy Ong, Patrick Du Souich

Journal:

Clinical Biochemistry

Year:

1985

Language:

english

File:

PDF, 514 KB

english, 1985

29

Acute moderate hypoxia reduces ethanol elimination in the conscious rabbit

Joanne Gavalakis, Patrick du Souich, Mahmoud Sharkawi

Journal:

Year:

1999

Language:

english

File:

PDF, 109 KB

english, 1999

30

Single-dose pharmacokinetics of ampicillin and tobramycin administered by hypodermoclysis in young and older healthy volunteers

N. CHAMPOUX, P. DU SOUICH, M. RAVAOARINORO, D. PHANEUF, J. LATOUR, J. R. CUSSON

Journal:

British Journal of Clinical Pharmacology

Year:

1996

Language:

english

File:

PDF, 306 KB

english, 1996

31

The effect of a strongly basic alkaloidal fraction of Rhazya stricta, a traditional medicinal plant, on cytochrome P450-mediated metabolism of theophylline in mice

A. O. El-Kadi, M. O. M. Tanira, B. H. Ali, A. K. Bashir, P. Du Souich

Journal:

Phytotherapy Research

Year:

2003

Language:

english

File:

PDF, 92 KB

english, 2003

32

Expression profile of NSDHL in human peripheral tissues

Marie Morimoto, Christèle du Souich, Joanne Trinh, Keith W. McLarren, Cornelius F. Boerkoel, Glenda Hendson

Journal:

Journal of Molecular Histology

Year:

2012

Language:

english

File:

PDF, 10.41 MB

english, 2012

33

Phenotypic and molecular characterization of a novel DCX deletion and a review of the literature

A Chou, C Boerkoel, C Du Souich, R Rupps

Journal:

Clinical Genetics

Year:

2009

Language:

english

File:

PDF, 493 KB

english, 2009

34

19p13.2 microduplication causes a Sotos syndrome-like phenotype and alters gene expression

AM Lehman, C du Souich, D Chai, P Eydoux, JL Huang, AK Fok, L Avila, J Swingland, AD Delaney, B McGillivray, D Goldowitz, B Argiropoulos, MS Kobor, CF Boerkoel

Journal:

Clinical Genetics

Year:

2012

Language:

english

File:

PDF, 1010 KB

english, 2012

35

Chondroitin Sulfate Inhibits the Nuclear Translocation of Nuclear Factor-κB in Interleukin-1β-Stimulated Chondrocytes

Claudia Jomphe, Mélanie Gabriac, Taben M. Hale, Lucie Héroux, Louis-Éric Trudeau, Denis Deblois, Eulalia Montell, Josep Vergés, Patrick Du Souich

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2008

Language:

english

File:

PDF, 212 KB

english, 2008

36

Tocainide kinetics and metabolism: Effects of phenobarbital and substrates for glucuronyl transferase

Elvin, Alfred T, Lalka, David, Stoeckel, Klaus, Souich, Patrick Du, Axelson, James E, Golden, Lawrence H, McLean, Allan J

Journal:

Clinical Pharmacology & Therapeutics

Year:

1980

Language:

english

File:

PDF, 481 KB

english, 1980

37

Tixocortol pivalate, a corticosteroid with no systemic glucocorticoid effect after oral, intrarectal, and intranasal application

Larochelle, P, Du Souich, P, Bolte, E, Lelorier, J, Goyer, R

Journal:

Clinical Pharmacology & Therapeutics

Year:

1983

Language:

english

File:

PDF, 440 KB

english, 1983

38

Enhancement of nadolol elimination by activated charcoal and antibiotics

Souich, P du, Caillé, G, Larochelle, P

Journal:

Clinical Pharmacology & Therapeutics

Year:

1983

Language:

english

File:

PDF, 426 KB

english, 1983

39

Effect of aminoglycosides on the disposition of thyroid hormones and thyroglobulin

Souich, Patrick Du, Pison, Cesar, Pedneault, Louise, Larochelle, Pierre, Morisset, Richard, Vega, Carlos, Phaneuf, Denis, Poisson, Michel

Journal:

Clinical Pharmacology & Therapeutics

Year:

1985

Language:

english

File:

PDF, 489 KB

english, 1985

40

Down-regulation of the hepatic cytochrome P450 by an acute inflammatory reaction: implication of mediators in human and animal serum and in the liver

Ayman O S El-Kadi, Hélène Maurice, Huy Ong, Patrick du Souich

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 314 KB

english, 1997

41

21-Aminosteroids prevent the down-regulation of hepatic cytochrome P450 induced by hypoxia and inflammation in conscious rabbits

Ahmed Galal, Patrick Du Souich

Journal:

British Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 163 KB

english, 1999

42

Cytochrome P450 inactivation by serum from humans with a viral infection and serum from rabbits with a turpentine-induced inflammation: the role of cytokines

Anne-Marie Bleau, Mihaela C Levitchi, Hélène Maurice, Patrick Du Souich

Journal:

British Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 193 KB

english, 2000

43

Hypoxia-induced down-regulation of CYP1A1/1A2 and up-regulation of CYP3A6 involves serum mediators

Caroline Fradette, Anne-Marie Bleau, Vincent Pichette, Nathalie Chauret, Patrick Du Souich

Journal:

British Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 372 KB

english, 2002

44

Hypoxia-inducible factor-1 and activator protein-1 modulate the upregulation of CYP3A6 induced by hypoxia

Caroline Fradette, Patrick du Souich

Journal:

British Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 361 KB

english, 2003

45

5-Hydroxytryptamine is biotransformed by CYP2C9, 2C19 and 2B6 to hydroxylamine, which is converted into nitric oxide

Caroline Fradette, Nobuharu Yamaguchi, Patrick Du Souich

Journal:

British Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 249 KB

english, 2004

46

Hepatic Extraction of Hexarelin, a New Peptidic GH Secretagogue, in the Isolated Perfused Rat Liver

Marie Roumi, Sylvie Marleau, Muny Boghen, Magnus Nilsson, Patrick Du Souich, Huy Ong

Journal:

Pharmaceutical Research

Year:

1997

File:

PDF, 488 KB

1997

47

First-Pass Metabolism of Diltiazem in Anesthetized Rabbits: Role of Extrahepatic Organs

Marc Lefebvre, Walid Homsy, Gilles Caillé, Patrick du Souich

Journal:

Pharmaceutical Research

Year:

1996

File:

PDF, 912 KB

1996

48

The Site of Absorption in the Small Intestine Determines Diltiazem Bioavailability in the Rabbit

Walid Homsy, Gilles Caillé, Patrick du Souich

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.02 MB

1995

49

Metabolism of Diltiazem in Hepatic and Extrahepatic Tissues of Rabbits:InVitroStudies

Walid Homsy, Marc Lefebvre, Gilles Caillé, Patrick du Souich

Journal:

Pharmaceutical Research

Year:

1995

File:

PDF, 1.05 MB

1995

50

Salbutamol disposition and dynamics in conscious rabbits: Influence of the route of administration and of the dose

Sylvie Perreault, Huy Ong, Patrick du Souich

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1992

Language:

english

File:

PDF, 896 KB

english, 1992

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